Endoglycosidases release oligosaccharides from glycoproteins or glycolipids. Endoglycosidases cleave polysaccharide chains between residues that are not the terminal residue.These products are most commonly used to remove glycans for analysis, or to obtain deglycosylated proteins for analysis.
Notable among these these is PNGase F, an asparagine amidase that releases intact N-glycans by cleaving bettern the innermost GlcNAc of the N-glycan and the asparagine (Asn) residue of the peptide the N-glycan is linked to.
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